Design of Enabling-Regenerative Materials

Programme 2014 - 2020 INTERREG V-A France - Belgium - The Netherlands - United Kingdom (Les Deux Mers / Two seas / Twee Zeeën)

Date of latest update: 2024-12-17

Description

Description (EN):

The objective of DERMA is to develop new interventions for the management and treatment of dermal ulcers and related skin conditions, including stomas. By addressing market and patient needs, as identified by our Observer Partners (OPs), the project will deliver advanced new technologies (incorporating marine sourced biopolymers) ready for exploitation by industry to manufacture improved products for the treatment of patients. It is expected that these enabling technologies will provide cost savings to the EU by improving the efficiency and success of wound management by healthcare providers.

Achievements (EN):

The DERMA project is developing novel dressing materials that can be used for the improved management of chronic dermal ulcers. In such wounds, where the dermal tissue is broken down by infection and inflammation, offensive odours are produced that are embarrassing for the patient, and these can lead to social isolation. Chronic wounds may also be subjected to a series of underlying infections that the body does not easily eradicate and that require clinical intervention. To meet these twin challenges of malodour production and infection, the project is developing two types of materials; the first to manage unpleasant odours from a wound, and the second to visually indicate the emergence of a developing infection. The materials to combat wound malodour have used activated carbon (AC) powder as the active ingredient. One form is a thin film made by combining AC with agarose from seaweed that has been treated to be flexible and elastic and thus able to easily fit with the contours of the skin. This material has been augmented to have a fluid handling capability to make it suitable for use on sloughy wounds which can otherwise cause damaging tissue maceration. AC for odour control has also been incorporated into very fine, electrospun fibres. By presenting the AC in this way, a relatively large surface area for odour removal will be achieved, making the odour removal process very efficient. These fibres are also highly water absorbent, of benefit for wound moisture control. These fibres also have a remarkable ability to release antimicrobial agents over extended periods, meaning that, in the form of a wound dressing, they could potentially be worn for longer than current antimicrobial forms. The odour capture studies have been augmented with the use of an electronic nose. The device can be used to identify and quantify odours. It is being evaluated for the detection of specific bacteria within foot ulcers, thereby informing the material development work, where the breakthrough of relevant odours is quantified. To indicate the presence of a bacterial infection, candidate polymers and colour-changing indicator dyes have been selected. The dyes change colour when exposed to growing bacteria. Work is focused on controlling the release of the dyes from the thin film and electrospun forms. An interesting development is the finding that one form of the dye has been found to inhibit the growth of Staphylococcus aureus, an important bacterium of chronic wounds.

Website: http://www.derma2seas.eu/

Delivered Outputs (EN):

The main outputs of the DERMA project consist in technologies with increased readiness levels for the treatment of dermal ulcers, peristomal inflammation, and related conditions in response to identified market and patient needs: - A prototype dressing for wound odour and infection control (TRL 3 to 5); and - A prototype dressing with a diagnostic indicator of early wound healing status (TRL 3 to 5). - Route to market action plans for an odour-adsorbing antimicrobial wound dressing and for a diagnostic wound dressing. Beneficiaries are elderly patients, cancer patients, diabetics, ostomates (all through improved treatment and quality of life), healthcare providers (better treatment options and cost savings), regional industry (boost for innovation, blue economy and sales). Check the “Outputs” section below to download related material and see “Main Achievements” section for further information about the achieved results.

Thematic information

Health and social services

Specific Objective: Increase the delivery of innovation in smart specialisation sectors

Thematic Objective: (01) strengthening research, technological development and innovation by:

Investment Priority:

(01b) promoting business investment in R&I, developing links and synergies between enterprises, research and development centres and the higher education sector, in particular promoting investment in product and service development, technology transfer, social innovation, eco-innovation, public service applications, demand stimulation, networking, clusters and open innovation through smart specialisation, and supporting technological and applied research, pilot lines, early product validation actions, advanced manufacturing capabilities and first production, in particular in key enabling technologies and diffusion of general purpose technologies

Partners (4)

Lead Partner: University of Brighton

Department: School of Pharmacy and Biomolecular Sciences

Address: Lewes Road, BN2 4GJ Brighton, United Kingdom

Legal status: public

Total budget: EUR 805 109.35

ERDF budget: EUR 483 065.61

Eurasanté

Name: Eurasanté

Department: Innovation Department

Address: 310 avenue Eugène Avinée, 59120 LOOS, France

Legal status: private

Total budget: EUR 227 258.70

ERDF budget: EUR 136 355.21

Universiteit Gent

Name: Universiteit Gent

Department: Polymer Chemistry & Biomaterials Group and the Department of Plastic & Reconstructive Surgery (PRS)

Address: Krijgslaan 281, S4-Bis, 9000 Ghent, Belgium

Legal status: public

Total budget: EUR 1 142 968.31

ERDF budget: EUR 685 781.00

University of Portsmouth

Name: University of Portsmouth

Department: Faculty of Creative and Cultural Industries

Address: Winston Churchill Avenue, PO1 2DJ Portsmouth, United Kingdom

Legal status: public

Total budget: EUR 392 419.35

ERDF budget: EUR 235 451.61

Partners map

Lead partner

Project partner

Summary

Project name (EN): Design of Enabling-Regenerative Materials

Project acronym: DERMA

Project start date: 2016-09-01

Project end date: 2020-11-30

Project status: closed

Total budget/expenditure: EUR 2 567 755.71

Total EU funding (amount): EUR 1 540 653.43

Total EU funding (co-financing rate): 0.60%

Co-financing sources:

Documents

Documents on this project are listed below, and organised by category. Please note field "Data source", attached to each document. Keep.eu users are free to use these documents as long as they mention the data source and keep.eu.

Videos / films

DERMA the documentary: Biomaterials In Action

Attachment type: link

Type of document: Video / film

Data source: http://www.interreg2seas.eu

Publication date: 2022-10-31

Document date: 2021-01-11

Languages: en

DERMA: Odour Capture Material CGI Animation

Attachment type: link

Type of document: Video / film

Data source: http://www.interreg2seas.eu

Publication date: 2022-10-31

Document date: 2021-01-06

Languages: en

DERMA: Diagnostic Material CGI Animation

Attachment type: link

Type of document: Video / film

Data source: https://www.derma2seas.eu/

Publication date: 2022-10-31

Document date: 2021-01-06

Languages: en

DERMA: Antimicrobial Material CGI Animation

Attachment type: link

Type of document: Video / film

Data source: https://www.derma2seas.eu/

Publication date: 2022-10-31

Document date: 2021-01-06

Languages: en

DERMA the documentary: Biomaterials In Action

Attachment type: link

Type of document: Video / film

Data source: https://www.derma2seas.eu/

Publication date: 2022-10-31

Document date: 2021-01-11

Languages: en

DERMA: The Patient-Clinician Experience

Attachment type: link

Type of document: Video / film

Data source: https://www.derma2seas.eu/

Publication date: 2022-10-31

Document date: 2021-01-06

Languages: en

DERMA Documentary : Biomaterials In Action

Attachment type: link

Type of document: Video / film

Data source: https://www.derma2seas.eu/

Publication date: 2022-10-31

Document date: 2020-11-26

Languages: en

Brochures / magazines / manuals

DERMA-Design of Enabling-Regenerative Materials

Attachment type: file

Type of document: Brochure / magazine / manual

Data source: https://www.derma2seas.eu/

Publication date: 2022-10-31

Document date: 2020-11-30

Languages: en

Attachment file: Download

Information regarding the data in keep.eu on the programme financing this project

Financing programme

2014 - 2020 INTERREG V-A France - Belgium - The Netherlands - United Kingdom (Les Deux Mers / Two seas / Twee Zeeën)

Last month that data in keep.eu was retrieved from the Programme's website or received from the Programme

2024-12-17

No. of projects in keep.eu / Total no. of projects (% of projects in keep.eu)

82 / 82 (100%)

No. of project partnerships in keep.eu / Total no. of project partnerships (% of project partnerships in keep.eu)

886 / 886 (100%)

Notes on the data

Information provided by the Programme in 2024-12.

Languages

Contact Form

Design of Enabling-Regenerative Materials

Description

Thematic information

Partners (4)

Partners map

Summary

Documents

Information regarding the data in keep.eu on the programme financing this project

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