Genetic Expertise Hub for improved cancer prevention and treatment services

Programme 2021 - 2027 Interreg VI-A NEXT Romania - Rep.Moldova

Date of latest update: 2025-06-12

Description

Description (EN):

GENE-CONNECT, is a collaborative project aimed at improving cancer prevention and treatment services in the Romania-Moldova region. The primary challenge in this area is the lack of uniformity in cancer diagnosis and treatment, leading to disparities in care quality. The project aims to address this by setting a new benchmark for cancer care in the region, focusing particularly on inherited cancer syndromes. The overall objective of GENE-CONNECT is to harmonize and elevate the standards of cancer diagnosis and treatment across the Romania-Moldova region. This will be achieved through technology standardization, professional training and capacity building, and the enhancement of healthcare services. The main outputs of the project include the establishment of uniform, cross-border standards for cancer diagnosis and treatment, the enhancement of healthcare professionals' skills and knowledge in genetic cancer diagnosis and treatment, and the improvement of healthcare infrastructure and services. The approach of the project involves a comprehensive, collaborative effort encompassing various key pillars such as harmonization of cancer diagnosis and treatment protocols, capacity building and professional development, upgrading healthcare infrastructure and services, promotion of integrated community care models, and cross-border collaboration and knowledge sharing. What makes this project new and original is its focus on inherited cancer syndromes and the use of advanced genetic testing methods. It also emphasizes the importance of cross-border collaboration and knowledge sharing in improving cancer care standards. Furthermore, it seeks to transition from institutional to community-based care models, thereby improving access to cancer care services, especially for remote and underserved communities.

Expected Achievements (EN):

O1: Implement unified diagnostic protocols for inherited cancer syndromes in Romania and Moldova, integrating Next Generation Sequencing into routine procedures, enhancing diagnostic accuracy, and improving patient outcomes. SO2: Elevate the expertise of healthcare professionals through comprehensive training programs, encouraging continuous learning and excellence in genetic cancer diagnostics and personalized treatment. SO3: Enhance cancer care quality by upgrading healthcare facilities and equipment in both countries, facilitating effective and efficient diagnosis and treatment, and improving patient outcomes and satisfaction. Together, these objectives will drive impactful change in cancer care across borders.

Project outputs: Cross-Border Knowledge Hub for Enhanced Cancer Care(EN)
- Enhanced Competence in Clinical Cancer Genetics(EN)
Cross-Border Standardization of Cancer Genetics Services (EN)

Thematic information

Health and social services Scientific cooperation Knowledge and technology transfer

Priority: (VI-A_Ro-Mo_2) Social Development across Borders

Priority specific objective: RSO4.5. Ensuring equal access to health care and fostering resilience of health systems, including primary care, and promoting the transition from institutional to family-based and community-based care

Priority policy objective (Interreg specific objective): PO4 A more social and inclusive Europe implementing the European Pillar of Social Rights

Type of intervention: 129 Health equipment

Partners (2)

Lead Partner: Instituția Medico-Sanitară Publică Institutul Oncologic

PIC (Participant Identification Code): 967152469

Partner’s ID if not PIC: 1003600151023

Department: Immunology and Medical Genetics Laboratory

Address: Nicolae Testimitanu, MD 2025 Chisinau, Moldova

Department address: Nicolae Testimitanu, MD 2025 Chisinau, Moldova

Legal status: public

Organisation type: Hospitals and medical centres

Website: http://www.onco.md

Total budget: EUR 258 946.42

Partner’s programme co-financing: EUR 233 051.77

Partner’s programme co-financing rate: 90.00%

Partner contribution: EUR 25 894.65

Institutul Regional de Oncologie Iași

Name: Institutul Regional de Oncologie Iași

Department: TRANSCEND department and Screening Department

Partner’s ID if not PIC: 29067408

Address: Str. G-ral Berthelot, 700483 Iasi, Romania

Department address: Str. G-ral Berthelot, 700483 Iasi, Romania

Legal status: public

Organisation type: Hospitals and medical centres

Website: https://www.iroiasi.ro

Total budget: EUR 181 418.50

Partner’s programme co-financing: EUR 163 276.65

Partner’s programme co-financing rate: 90.00%

Partner contribution: EUR 18 141.85

Partners map

Lead partner

Project partner

Summary

Project name (EN): Genetic Expertise Hub for improved cancer prevention and treatment services

Project acronym: GENE-CONNECT

Project ID: ROMD00649

Project start date: 2025-03-29

Project end date: 2026-09-28

Project status: ongoing

Relevant linked projects:

"Changes in human colonic microbiome in antibiotic generated stress "/ – “COLONSTRESS” - funded through Joint Cooperation Programme Romania-Moldova 2014-2020. (EN) | The aim of the project "Changes in human colonic microbiome in antibiotic generated stress " was to compare microbiome differences in two populations that are exposed to different antibiotic protocols and to better understand the impact of broad-spectrum antibiotics as a driving force for the development of resistance.
The project, through its objectives and results, developed two superior molecular diagnostic and research laboratories, dedicated to oncological diagnosis and treatment.
The results of this project included the validation of a common platform for biomolecular research, the qualification of the training of the personnel involved in it, a new protocol for prophylactic antibiotic treatment, including a report on antibiotic-induced changes and the response of the human colonic microbiome to different stress situations.
The project "Changes in human colonic microbiome in antibiotic generated stress " improved the condition of the innovation framework for cross-border research actions in the field of the human microbiome.
(EN), Network of Excellence for Diagnosis and Research in Lung Cancer Disease”/”-LUNGNEX” - funded through Joint Cooperation Programme Romania-Moldova 2014-2020. (EN) | Project scope was to develop translational and personalized medicine approaches in the Republic of Moldova. The main long-term benefit of this cooperation was the development of two superior molecular diagnostics and research laboratories, capable of further training staff in metagenomic DNA sequencing techniques and accumulating theoretical and practical knowledge of NGS Ion Torrent și Illumina technologies.
Based on the new technology, we aimed to produce a cross-border group collaboration of excellence for parallel DNA sequencing. Both medical institutions (partners) used DNA sequencing equipment resulting in the creation of a common platform for synergistic work and with compatible protocols
The most important objective of this project was to build a team by integration of most relevant biomedical and clinical diagnostic and research segments in the cross-border area. The multidisciplinary team was able to manage high performance technique output information in order to use in diagnostic, treatment initiation, disease management and prognostic. Joint teams were created and together designed a strategic action plan for developing an integrated lung cancer research network that with the purpose to improve innovation framework conditions in the field. (EN)

Total budget/expenditure: EUR 440 364.92

Total EU funding (amount): EUR 396 328.42

Total EU funding (co-financing rate): 90.00%

Co-financing sources:

Investments, deliverables, policy contributions

(bullets are inserted automatically and may be incorrectly placed)

Deliverables:

1 PM Handbook
Periodic report
1 Project Monitoring and Evaluation Plan
1 Quality assurance Plan
1 Comprehensive Communication Strategy and Materials
1 set of Dissemination Reports and Materials
Upgraded Lab Infrastructure composed of 2 advanced genetic equipment procured and installed
1 Pilot Screening Data and Outcomes Analysis Report
1 Validated Screening Workflow with Integrated Quality Assurance
1 set of Standardized Cross-Border Protocols and Procedures
1 Training Needs Assessment Report
1 Specialized Training Curricula and Materials
8 Workshop/Seminar Reports
1 Exchange Program Records
1 Community Care Model Framework
1 Enhanced Screening Services Report
1 Knowledge Hub Portal
1 Screening Database

Contribution to wider strategies and policies:

EUStrategyDanubeRegion The GENE-Connect project aligns with the EU Strategy for the Danube Region (EUSDR) 2021-2027 by enhancing healthcare quality and cooperation across the region. It supports the EUSDR's objectives of improving the quality of life, fostering health, and ensuring environmental sustainability. The project's focus on standardizing cancer care, promoting professional training, and enhancing healthcare infrastructure directly contributes to regional development, innovation, and social integration goals of the EUSDR. This alignment demonstrates GENE-Connect's commitment to regional development priorities set by the EU
Other The GENE-CONNECT project contributes to the EU Cancer Plan by aligning with its objectives and priorities. The project focuses on genetic cancer research and treatment, supporting efforts to reduce cancer incidence, improve public health, and increase cancer screening uptake. GENE-CONNECT promotes healthy lifestyles, health literacy, and revises the European Code against Cancer, contributing to cancer prevention. It also supports early detection initiatives by promoting equal access to screening, improving data management, and enhancing screening program quality. The project leverages advanced genetic testing equipment and promotes collaborative research, aligning with the EU's emphasis on research and innovation in cancer prevention, treatment, and care. GENE-CONNECT actively supports the EU Cancer Mission, contributing to responsible data sharing, Open Science, and innovative solutions in personalized cancer care. Overall, the project's focus on genetic cancer research and treatment makes a valuable contribution to the EU Cancer Plan's goals of combating cancer and improving cancer control.
Other EU Digital Strategy (Digital Decade) - Advancing Digital Transformation - The project leverages advanced genetic testing equipment and promotes collaborative research, aligning with the EU's emphasis on research and innovation in the digital transformation of healthcare. By utilizing digital technologies in genetic research and treatment, the project contributes to the overall digitalization of the healthcare sector.
Data-driven Approach - The project's focus on genetic data analysis and research aligns with the EU's emphasis on data-driven approaches. By utilizing and analyzing large datasets in genetic research, the project contributes to the EU's goal of making the EU a role model for a society empowered by data.
Digital Health Initiatives - The project's efforts to enhance oncological diagnosis and treatment through genetic research align with the EU's focus on digital health initiatives. By utilizing digital technologies in healthcare, such as genetic testing and analysis, the project contributes to the EU's goal of achieving better healthcare outcomes through digital innovation.
Other EU Green Deal - Transition to a Sustainable Economy - The project's focus on genetic research and treatment aligns with the EU's goal of transitioning to a sustainable economy. By utilizing advanced technologies and promoting research in genetic cancer treatment, the project contributes to the development of sustainable healthcare practices.
Environmental Protection - promoting sustainable healthcare practices and reducing the reliance on traditional cancer treatment methods that may have negative environmental consequences
Innovation and Research - By leveraging advanced genetic testing equipment and promoting collaborative research, the project contributes to the EU's goal of fostering innovation and technological advancements in healthcare.
Just and Sustainable Transition - promoting equal access to genetic cancer research and treatment, potentially benefiting marginalized communities
Other GENE-CONNECT contributes to the Romania Cancer Plan by addressing key challenges and priorities outlined in the plan. While specific information about the project's direct contribution to the Romania Cancer Plan is not available in the search results, we can infer its alignment based on the project's focus on genetic cancer research and treatment. Here's a summary of how the GENE-CONNECT project contributes to the Romania Cancer Plan:
1. Improving Cancer Diagnosis and Treatment: The project's focus on genetic research and treatment aligns with the Romania Cancer Plan's objective of improving cancer diagnosis and treatment. By leveraging advanced genetic testing equipment and promoting collaborative research, the project contributes to enhancing the accuracy and effectiveness of cancer diagnosis and treatment methods.
2. Addressing High Cancer Mortality Rates: Romania has higher cancer mortality rates compared to the EU average. The GENE-CONNECT project's efforts to enhance oncological diagnosis and treatment directly contribute to addressing this issue by improving patient outcomes and reducing disparities in cancer care.
3. Supporting Preventive Measures: The project indirectly supports preventive measures by focusing on genetic research. While the Romania Cancer Plan may have a stronger emphasis on therapy and treatment, the project's contribution to genetic research can provide valuable insights for preventive measures in the long term.
4. Enhancing Collaboration and Knowledge Sharing: The GENE-CONNECT project's emphasis on collaborative research aligns with the Romania Cancer Plan's objective of improving collaboration and knowledge sharing among experts. By fostering collaboration and sharing research findings, the project contributes to the overall advancement of cancer care in Romania.
Other Moldova National Cancer Strategy - GENE-CONNECT supports the Republic of Moldova’s cancer strategy by targeting key concerns alongside with the goals stated in the project’s plan, having the following overview:
1. Optimizing Cancer Detection and Treatment: The Republic of Moldova Cancer Plan's goal of improving cancer diagnosis and treatment is in line with the project's focus on genetic research and treatment. The project advances the precision and efficacy of cancer detection and treatment approaches by utilizing cutting-edge genetic testing technology and encouraging cooperative research.
2. Combating Elevated Cancer Mortality: Similar to Romanian, the cancer death rate in the Republic of Moldova is greater than the average for the region. By enhancing patient outcomes and decreasing inequities in cancer care, the GENE-CONNECT project's efforts towards better oncological diagnosis and therapy proactively tackle this problem.
3. Promoting Preventative Strategies: The project's emphasis on genetic research serves to subsequently encourage preventive actions. Long-term preventive strategies can benefit greatly from the project's contribution to genetic studies, giving also priority to diagnosis and care.
4. Strengthening Cooperative Efforts: Improving expert interaction and sharing of information is a goal of the Republic of Moldova Cancer Strategy, which is in line with the GENE-CONNECT initiative's focus on joint research. The project enhances the management of cancer in the Republic of Moldova through encouraging cooperation and disseminating research findings.

Programme Common Output Indicator:

RCO 081 - Participations in joint actions across borders, Measurement unit:
RCO 087 - Organisations cooperating across borders, Measurement unit:
RCO 069 - Capacity of new or modernised health care facilities, Measurement unit:

Programme Common Result Indicator:

RCR 084 - Organisations cooperating across borders after project completion, Measurement unit:
RCR 073 - Annual users of new or modernised health care facilities, Measurement unit:
RCR 085 - Participations in joint actions across borders after project completion, Measurement unit:

Project part of European Union Macro-Regional or Sea Basin Strategy: EUSDR

Information regarding the data in keep.eu on the programme financing this project

Financing programme

2021 - 2027 Interreg VI-A NEXT Romania - Rep.Moldova

Last month that data in keep.eu was retrieved from the Programme's website or received from the Programme

2025-06-12

No. of projects in keep.eu / Total no. of projects (% of projects in keep.eu)

20 / 20 (100%)

No. of project partnerships in keep.eu / Total no. of project partnerships (% of project partnerships in keep.eu)

51 / 51 (100%)

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