Health for Dairy Cows

Programme 2014 - 2020 INTERREG V-A France - Belgium - The Netherlands - United Kingdom (Les Deux Mers / Two seas / Twee Zeeën)

Date of latest update: 2025-03-29

Description

Description (EN):

The purpose of our project is to reduce Cryptosporidium outbreaks impact in cattle and milk production across the 2 seas area. We aim to improve the sanitation quality of production by a bottom up approach, to increase in situ detection tools and to accelerate the selection of anti-cryptosporidium drugs. We will measure the economic impact of our project developments and accelerate the transferability of our methods and technological innovations to industries and stakeholders.

Achievements (EN):

The H4DC consortium was able to successfully complete the project and achieve the objectives and results that were initially planned. 20 farms in France, 17 farms in Belgium and 20 farms in the Netherlands were recruited. Three sampling campaigns were done and enabled the presence of Cryptosporidium parasite population (leading to 2 scientific articles and 2 presentations in international scientific conferences). Following an analysis of the scientific literature on the risk factors leading to the dissemination of the parasite in herds, partners were able to advise breeders on changes to their practices, and 2 years later they evaluated the benefits for breeders. To build a test kit, a set of Cryptosporidium parasite proteins was synthesized. Antibodies targeting these molecules were generated and used in new test strips. The H4DC partnership was also able to build and test a drug screening device associated with a complete set up to analyse and record electric responses of cells when infected by parasites. The development of an Artificial intelligence software and the specific training of a neuronal based network accelerated microscopic observation used to assess drug efficiency and automated a process that was initially carried out manually. This approach is now being used to test additives supplied by a private company. Two biopharmaceutical companies have expressed interest in accessing these technologies to carry out tests for their own anti-parasitic drugs. Dissemination of the project was impeded by travel restriction during covid lockdown, but H4DC partners were able to create a wide range of contacts (Farmers, Veterinarians, Biotechnological/Biopharmaceutical companies). Since September 2022, one codirected PhD project has been launched between partners UK & France. This will guarantee the continuation of the project beyond its closing date. Two market studies and two business models have been done. Additionally, during the H4DC project, samples collected in farms were also used to study the impact of the metabolome changes due to parasite infection. The genetic analysis of calves was also done to detect if specific genes could represent parasite contamination risk factors. Such results are essential for genetic selection and could have an important economic impact for breeders.

Website: https://www.interreg2seas.eu/

Delivered Outputs (EN):

The main outputs of the H4DC project are: - A number of pilot farms set up by a bottom-up approach; - An easy-to-use pilot in-situ parasite detection system; - A cellular based device prototype for drug screening; - A transferability and market uptake strategy. Check the “Outputs” section below to download related material and see “Main Achievements” section for further information about the achieved results.

Thematic information

Agriculture and fisheries and forestry

Specific Objective: Increase the delivery of innovation in smart specialisation sectors

Thematic Objective: (01) strengthening research, technological development and innovation by:

Investment Priority:

(01b) promoting business investment in R&I, developing links and synergies between enterprises, research and development centres and the higher education sector, in particular promoting investment in product and service development, technology transfer, social innovation, eco-innovation, public service applications, demand stimulation, networking, clusters and open innovation through smart specialisation, and supporting technological and applied research, pilot lines, early product validation actions, advanced manufacturing capabilities and first production, in particular in key enabling technologies and diffusion of general purpose technologies

Partners (7)

Lead Partner: Junia

Department: Agriculture Department

Address: Boulevard Vauban, 59043 Lille, France

Legal status: private

Total budget: EUR 1 102 417.80

ERDF budget: EUR 661 450.68

Zuidelijke Land- en Tuinbouw Organisatie (ZLTO)

Name: Zuidelijke Land- en Tuinbouw Organisatie (ZLTO)

Department: Department craftsmanship and entrepreneurship

Address: Onderwijsboulevard 225, 5223 DE Den Bosch, Netherlands

Legal status: private

Total budget: EUR 254 484.76

ERDF budget: EUR 152 690.86

University of East Anglia

Name: University of East Anglia

Department: Biomedical Research Centre

Address: UEA, Earlham Road, NR4 7TJ Norwich , United Kingdom

Legal status: public

Total budget: EUR 368 307.77

ERDF budget: EUR 220 984.66

SelasCVE

Name: SelasCVE

Department: Ruminants division

Address: 156 avenue Fleming, 62400 Béthune, France

Legal status: private

Total budget: EUR 100 017.79

ERDF budget: EUR 60 010.68

Inagro

Name: Inagro

Department: Animal Production department

Address: Ieperseweg 87, 8800 Rumbeke, Belgium

Legal status: public

Total budget: EUR 238 206.76

ERDF budget: EUR 142 924.06

University of Kent

Name: University of Kent

Department: School of Biosciences

Address: Stacey Building Giles Lane, CT2 7NJ Canterbury, United Kingdom

Legal status: public

Total budget: EUR 1 307 129.98

ERDF budget: EUR 784 278.00

Centre National de la recherche Scientifique (CNRS)

Name: Centre National de la recherche Scientifique (CNRS)

Department: CNRS/DR18

Address: 2,Rue des canonniers, 59046 Lille, France

Legal status: public

Total budget: EUR 62 216.67

ERDF budget: EUR 37 330.00

Partners map

Partners and Projects info

Zuidelijke Land- en Tuinbouw Organisatie (ZLTO)

Health for Dairy Cows

Partners and Projects info

University of East Anglia

Health for Dairy Cows

Partners and Projects info

SelasCVE

Health for Dairy Cows

Partners and Projects info

Inagro

Health for Dairy Cows

Partners and Projects info

University of Kent

Health for Dairy Cows

Partners and Projects info

Centre National de la recherche Scientifique (CNRS)

Health for Dairy Cows

Partners and Projects info

Junia

Health for Dairy Cows

Lead partner

Project partner

Summary

Project name (EN): Health for Dairy Cows

Project acronym: H4DC

Project start date: 2019-03-01

Project end date: 2023-03-31

Project status: closed

Total budget/expenditure: EUR 3 432 781.53

Total EU funding (amount): EUR 2 059 668.94

Total EU funding (co-financing rate): 0.60%

Co-financing sources:

Documents

Documents on this project are listed below, and organised by category. Please note field "Data source", attached to each document. Keep.eu users are free to use these documents as long as they mention the data source and keep.eu.

Videos / films

Introduction to the H4DC project

Attachment type: link

Type of document: Video / film

Data source: http://www.interreg2seas.eu

Publication date: 2023-10-23

Document date: 2020-04-01

Languages: en

Information regarding the data in keep.eu on the programme financing this project

Financing programme

2014 - 2020 INTERREG V-A France - Belgium - The Netherlands - United Kingdom (Les Deux Mers / Two seas / Twee Zeeën)

Last month that data in keep.eu was retrieved from the Programme's website or received from the Programme

2024-12-17

No. of projects in keep.eu / Total no. of projects (% of projects in keep.eu)

82 / 82 (100%)

No. of project partnerships in keep.eu / Total no. of project partnerships (% of project partnerships in keep.eu)

886 / 886 (100%)

Notes on the data

Information provided by the Programme in 2024-12.

Languages

Contact Form

Health for Dairy Cows

Description

Thematic information

Partners (7)

Partners map

Summary

Documents

Information regarding the data in keep.eu on the programme financing this project

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